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Drury Plaza Hotel Cape Girardeau Conference Center Tickets

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About Drury Plaza Hotel Cape Girardeau Conference Center

Welcome to Drury Plaza Hotel Cape Girardeau Conference Center, a full-service venue that combines convenient meeting spaces with on-site dining, free parking, and easy access to Cape Girardeau’s attractions. Whether you’re planning a conference, banquet, or corporate retreat, we’ve got you covered with flexible room configurations and modern amenities. Secure your seats for your next event with help from a connected partner you can trust.

Address: 3351 Percy Drive, Cape Girardeau, MO 63701. The property features a conference center with over 14,000 square feet of meeting space, including the Mississippi Center, which is among the largest rooms for theater-style setups. The Southerner by Tractors provides on-site dining options, making this a convenient all-in-one destination for attendees, planners, and vendors.

Transit and arrival are straightforward in Cape Girardeau. The area is served by CGCTA fixed-route buses (free), SEMO campus routes, and nearby Greyhound/FlixBus stops for travelers arriving from other cities. Parking is complimentary for guests staying at the hotel or attending events in the conference center. We’ve gathered seating charts and setup options to help you plan with confidence.

Nearby hotels, dining, and services complement your event experience. We highlight affiliate-friendly options for lodging and meals to simplify planning. For any gathering—whether a large conference or a smaller board meeting—this Drury property provides a reliable, no-fuss backdrop with versatile spaces, on-site catering, and straightforward access to Cape Girardeau’s local amenities.

If you’re ready to book, contact us to secure your preferred dates, confirm room blocks, and review the interactive floor plans and setup charts available on the venue’s Cvent page. We’re here to help you navigate capacities, seating styles, and nearby hospitality partners to make your event seamless.

Good to know

Seating, Parking & Venue Information

  • Address: 3351 Percy Drive, Cape Girardeau, MO 63701.
  • Venue type: Full-service Drury hotel with an attached conference center and on-site restaurant history (The Southerner by Tractors).
  • Total meeting space: hotel ~1,400 sq ft; Conference Center ~14,000+ sq ft (official sources vary between 14,000 and 14,652 sq ft).
  • Largest room: Mississippi Center (~14,453 sq ft) with theater seating up to ~1,200 (per Cvent) or up to ~1,450 in some configurations (per Drury capacity pages).
  • Other rooms: Truman, Missouri, Cape Rock, Capaha, etc., with varying banquet, theater, and classroom capacities (multiple rooms listed on the Drury capacities page).
  • Parking: Free parking during stay.
  • Seating chart/draft floor plans: Available via the venue’s Cvent page with interactive floor plans and setup charts.
  • Transit options: CGCTA fixed-route buses (free); SEMO campus routes; nearby Greyhound/FlixBus stops (Cape Girardeau).
  • Nearby hotels: Drury Inn & Suites Cape Girardeau (3303 Campster Dr); Hampton Inn I-55 East; Holiday Inn Express & Suites Cape Girardeau I-55; Pear Tree Inn Cape Girardeau Medical Center; Courtyard by Marriott/Cape Girardeau Downtown (various options).
  • Notable events hosted: Department of Missouri conventions (e.g., 2025) and local events such as Books By The River (2026) at the Drury Plaza Cape Girardeau; venue actively used for meetings, banquets, and conferences.