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SERUM at PRYSM Nightclub Tickets

Location
Chicago Venue Guide, Se

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The venue

About SERUM at PRYSM Nightclub

SERUM at PRYSM Nightclub in Chicago is a dynamic hybrid venue that blends nightclub energy with live music across three distinct spaces: the Main Room, Mezzanine, and the 2,500 sq ft No.9 Champagne Lounge. Located at 1543 N Kingsbury St, this 850-capacity venue spans 10,000 sq ft and offers a versatile setting for high-energy DJ sets, live performances, and intimate gatherings. Whether you’re planning a headline show or a private night out, we’ve got you covered with practical seating info, easy-access parking, transit details, and nearby hotel and dining options to suit any traveler or local.

PRYSM’s proximity to major Red Line stops (North/Clybourn) and multiple bus routes (such as 72 and 8) makes public transit a convenient choice. For drivers, privately run valet sits adjacent to the club, with limited street parking available. If you’re visiting from out of town, explore nearby hotels like Hyatt Place Chicago/Wicker Park, Hotel Lincoln, Found Hotel Chicago River North, Ace Hotel Chicago, and The Godfrey Hotel Chicago. We highlight affiliate hotel and restaurant partners to help you secure comfortable stays and easy dining options near the venue. Upcoming notable SERUM events include Vintage Culture, John Digweed + CIOZ, Chris Liebing + BAUGRUPPE90, SERUM 039 He.She.They, and more. Secure your seats and plan your visit with confidence—SERUM and PRYSM have you covered.

Good to know

Seating, Parking & Venue Information

  • Address: 1543 N Kingsbury St, Chicago, IL 60642
  • Capacity: 850 total (Main Room, Mezzanine, No.9 Champagne Lounge) across 10,000 sq ft
  • Venue type: Hybrid nightclub / live-music venue with three distinct spaces
  • Seating/chart: Main Room + Mezzanine on two levels and No.9 Champagne Lounge (2,500 sq ft) with its own entrance and bar
  • Parking: Privately run valet adjacent to the club; limited street parking; public transit encouraged
  • Transit: Near Red Line North/Clybourn; several bus routes (e.g., 72, 8); Armitage/Grand stops nearby
  • Nearby hotels (example options): Hyatt Place Chicago/Wicker Park, Hotel Lincoln, Found Hotel Chicago River North, Ace Hotel Chicago, The Godfrey Hotel Chicago
  • Notable SERUM events hosted: Vintage Culture (Sept 27, 2024); John Digweed + CIOZ (Sept 26, 2025); Chris Liebing + BAUGRUPPE90 (Oct 17, 2025); SERUM 039 He.She.They (Dec 8, 2023); Gaskin + Kepler (Dec 5, 2025)